EFFECTS OF METABOLIC INHIBITORS ON PLANARIAN REGENERATION
نویسندگان
چکیده
منابع مشابه
Berberine exposure triggers developmental effects on planarian regeneration
The mechanisms of action underlying the pharmacological properties of the natural alkaloid berberine still need investigation. Planarian regeneration is instrumental in deciphering developmental responses following drug exposure. Here we report the effects of berberine on regeneration in the planarian Dugesia japonica. Our findings demonstrate that this compound perturbs the regenerative patter...
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The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and proportion (morphallaxis). Because blastemas do not repla...
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While tissue regeneration is typically studied using standard injury models, in nature injuries vary greatly in the amount and location of tissues lost. Planarians have the unique ability to regenerate from many different injuries (including from tiny fragments with no brain), allowing us to study the effects of different injuries on regeneration timelines. We followed the timing of regeneratio...
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ژورنال
عنوان ژورنال: The Biological Bulletin
سال: 1963
ISSN: 0006-3185,1939-8697
DOI: 10.2307/1539365